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1.

論文(リポジトリ)

論文(リポジトリ)
西巻, 正 ; 畠山, 勝義 ; 梨本, 篤 ; 宮下, 薫 ; 藍澤, 喜久雄 ; 吉川, 時弘 ; 若桑, 隆二 ; 長谷川, 正樹 ; 朝倉, 均
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  115  pp.318-326,  2001-07.  新潟医学会
本文リンク: http://hdl.handle.net/10191/48294
概要: Incidence and severity of refux esophagitis and their influence upon quality of life were assessed using a questionnaire in 3528 patients who had undergone gastrectomy for gastric cancer in 56 hospitals in Niigata prefecture. Reflux esophagitis-related symptoms manifested in 84.7% of those patients. Heart burn and regurgitation frequently developed and reduced quality of life postoperatively. Proximal gastrectomy, as well as total gastrectomy, and jejunal interposition were associated with high incidences of reflux-related symptoms. Overall, quality of life of the patients improved according to the lapse of time after gastrectomy although incidences of reflux esophagitis-related symptoms were unchanged by the time lapse. 続きを見る
2.

論文(リポジトリ)

論文(リポジトリ)
大谷, 哲也 ; 齋藤, 英樹 ; 片柳, 憲雄 ; 藍沢, 喜久雄 ; 山本, 睦生 ; 藍沢, 修
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  113  pp.404-410,  1999-09.  新潟医学会
本文リンク: http://hdl.handle.net/10191/46836
概要: This study was conducted to clarify the safety and efficacy of laparoscopic cholecystectomy. A total of 443 consecutive laparoscopic cholecystectomies were performed between March, 1992 and October, 1998 at Niigata City General Hospital. The overall conversion rate from laparoscopic to open cholecystectomy was 7.9% (35). Without these 35, two patients group were compared: the initial 200 cases and the late 208 cases. The average postoperative length of hospital stay was 4.9 days for the initial 200 cases and 4.6 days for the late 208 cases. The average operative time for the late 208 cases was 74 min., which was significantly shorter (p<0.001) than the time of 87 min. for the initial 200 cases. Significant morbidity occurred in 3.6% of the 443 patients, including bile duct injuries (6), bile leak (4), vascular injury (1), small bowel injury (1), and the others (5). The conversion to laparotomy for the treatment of a complication was 1.8% (8). The re-laparotomy was required for a complication in 3, one of who died of pulmonary infarction. We analyzed quality-of-life indicators for 37 unselected patients to clarify the feasibility of laparoscopic cholecystectomy. Postoperative pain was well controlled in 97% of the patients. Eighty five % of the patients returned to their jobs within 20 days after operation. Although some specific complications are associated with laparoscopic approach, laparoscopic cholecystectomy shows its overall safety and efficacy. Adequate training and experience of laparoscopic cholecystectomy is required for prevention of these complications. 続きを見る
3.

論文(リポジトリ)

論文(リポジトリ)
小池, 正
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  111  pp.133-136,  1997-03.  新潟医学会
本文リンク: http://hdl.handle.net/10191/44490
概要: Although the majority of adults with acute leukemia obtain a complete remission with current induction therapies, most of them relapse within 1-2 years. In an attempt to improve on these discouraging results, we have begun to offer bone marrow transplanataion to patients with HLA-identical siblings. BMT long-term survivors appear to demonstrate a quality of life that is slightly lower than that of chemotherpy long-term survivors. 続きを見る
4.

論文(リポジトリ)

論文(リポジトリ)
島村, 公年 ; 畠山, 勝義 ; 須田, 武保 ; 酒井, 靖夫
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  111  pp.142-146,  1997-03.  新潟医学会
本文リンク: http://hdl.handle.net/10191/44492
概要: Recently, function-preserving surgery has become more widely applied to patients with rectal cancer. Compared with abdom ioperineal resection, sphincter-saving procedure generally leads to an improved quality of life(QOL). However, straight colo-anal anastomsis(St type)for extremely low rectal carcinoma often causes a deterioration. Therefore, we have performed colonic J pouch-anal anastomosis(J type)since 1988. Forty patients who received the J type and 14 who received the St type are discussed. Mean daily stool frequency was 2.4 at 12 months after surgery in the J group, significantly lower than 5.0 in the St group. Frequent bowel movements and urgency placed restrictions on daily life in 29% of the St group, while there were no severe restrictions in the J group. An increased number of patients are undergoing autonomic nerve-preserving procedures, and good functional results have been obtained. The incidence of urinary dysfunction requiring consultation with a urologist was lower in the autonomic nerve-preserving group(3.4%)than in the non-preserving group(34.8%). Some sexual dysfunction was found in 14.3% of the autonomic nerve-preserving group, and in 92.3% of the non-preserving group. These results that the sphincter and autonomic nerve-preserving procedures produce good postoperative QOL. 続きを見る
5.

論文(リポジトリ)

論文(リポジトリ)
R.M.A., CHAMIKA ; Kobayashi, Keiko ; Narita, Taichi ; Saito, Tomoko
出版情報: 新潟大学保健学雑誌 — 新潟大学保健学雑誌.  13  pp.11-17,  2016-09.  新潟大学医学部保健学科
本文リンク: http://hdl.handle.net/10191/44138
概要: Lifestyle and health behavior are known risk factors for non-communicable diseases (NCD), and they can\naffect quality o f life (QOL). University students are future decision makers in institutions, societies, and countries. Thus,\nthe objectives of this study were to examine the reality of the lifestyles, health behaviors, and QOL of university students\nand to clarify the relationship between their health behaviors and QOL. The sample was 199 students at “A” University,\nin grades of first-year to fourth-year during the academic year 2014–15. A self-administered questionnaire assessed the\ndemographic variables, health statuses, lifestyles, health behaviors, and QOL of the students. The amount of time spent\nwatching television was higher among students living alone. Female students had higher amounts of study time and a\ngreater prevalence for adequate sleep (7–8 hours) than their counterparts. Regular exercise was higher among male\nstudents. Alcohol consumption and smoking were higher among male students, and students living with families ate\nbreakfast regularly. There was weak positive correlation between WHO Quality of Life-BREF and Breslow’s health\nhabits. This study showed that effective health education that considered differences of gender and family condition is especially relevant for the promotion of their health because the QOL at this phase of development creates a foundation for health and QOL in late adulthood. 続きを見る
6.

論文(リポジトリ)

論文(リポジトリ)
畑山, 潤治
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  102  pp.402-404,  1988-07.  新潟医学会
本文リンク: http://hdl.handle.net/10191/40854
概要: In Japan a welfare for the aged has been developed by Low for the welfare of the aged which enacted in 1963. This low provided three kinds of institution for the elderly i.e. Home with moderate fee, Nursing home and Special nursing home. These institutions have been increased by construction year after year. Today in Nagaoka, a plan of new institution for the patient who needs terminal nursing and care is being embodied by medical care staffs, social welfare institutional care staffs, Buddhist priests and other persons. This institution was named Vihara. It means a place of rest or a temple for Buddhist in Sanskrit. We hope to establish a manner of desirable terminal nursing and care for Japanese supported by Buddhistical standpoints. 続きを見る
7.

論文(リポジトリ)

論文(リポジトリ)
佐藤, 豊
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  103  pp.893-900,  1989-11.  新潟医学会
本文リンク: http://hdl.handle.net/10191/41454
概要: In the field of rehabilitation medicine, during the past two decades rehabilitation goal has changed from getting independency in activities of daily living (ADL) to getting higher quality of life (QOL). On the evaluation of the disabled people, impairment, disability and handicaps must be always considered, in order to getting higher quality of life the most important things are to make much improvement in the handicap level, not in the impairment nor disability level. In the patient with spinal cord injury the most paraplegics and quadriplegics whose injury level are lower than C-6 can be independent in ADL and are able to drive a car and go back to jobs and enjoy their lives with some recreational activities and sports with wheelchair. But the quadriplegics whose injury level are higher than C-5 will be mostly dependent in ADL and will become partially independent in ADL by using environmental control system (ECS) and micro-computer, so we must encourage the patients to use the ECS and micro-computer that they will be able to participate in creative activities like to write something, to call somebody, to put on TV or radio etc. In the patient with cerebral vascular accident, the elderly patients with CVA can be independent in ADL and go back to their home and take some role at home, the younger patients with CVA can be independent in ADL and must be able to go back to jobs and to enjoy sports and recreation activities or leisures. 続きを見る
8.

論文(リポジトリ)

論文(リポジトリ)
森田, 昌宏 ; 須賀, 良一 ; 滝沢, 謙二
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  103  pp.901-910,  1989-11.  新潟医学会
本文リンク: http://hdl.handle.net/10191/41457
概要: Psychiatrists have been confronted with a difficult task to help psychiatric patients adequately adapt to their social environments. Thus, it is necessary for psychiatrists to make efforts persistently to improve Quality of Life in psychiatric patient. The present paper describes two types of problems concerning QOL from the viewpoint of Consultation-Liaison Psychiatry. The first problem frequently occurs in the case of chronic schizophrenia associated with severe physical illness. There are some obstacles resulted in settings of medical and surgical treatements for their physical illness, since schizophrenic symptoms (loss of spontaneity, disturbance of reality-testing and so on) injure their ability of cooperating with medical staffs. For a successful treatment on their physical complications, physicians should ask psychiatrist for collaboration and set up an adequate goal of treatment and rehabilitation inconsideration of their mental and physical aspects of disabilities. The second is psychosocial problems, including a refusal to medical treatments, an interpersonal trouble with the medical staffs, a suicidal act and so on, that sometimes occur in the patients suffering from chronic and severe physical illness. It is useful to apply psychiatric approach to a solution of these problems. In this approach each patient is appreciated comprehensively as an unique existence who has his own personality and life, and treated with focusing on the therapeutic relation between patient and therapist. 続きを見る
9.

論文(リポジトリ)

論文(リポジトリ)
小林, 正治 ; Kobayashi, Tadaharu
出版情報: 新潟歯学会雑誌.  46  pp.57-68,  2016-12.  新潟歯学会
本文リンク: http://hdl.handle.net/10191/0002000552
10.

学位論文(リポジトリ)

学位
Maruyama, Katsuya
出版情報: 2017-03-23.  新潟大学
本文リンク: http://hdl.handle.net/10191/47573
概要: The aim of this study was to prospectively assess 5-year health-related quality of life (HRQOL) of patients treated with carbon ion radiotherapy (C-ion RT) for clinically localized prostate cancer. A total of 417 patients received carbon ion radiotherapy at a total dose of 63-66 Gray-equivalents (GyE) in 20 fractions over 5 weeks, and neoadjuvant and adjuvant androgen deprivation therapy (ADT) were administered for intermediate and high-risk patients. A HRQOL assessment was performed at five time points (immediately before the initiation of C-ion RT, immediately after, and at 12, 36 and 60 months after completion of C-ion RT) using Functional Assessment of Cancer Therapy (FACT) questionnaires. FACT-G and FACT-P scores were significantly decreased; however, the absolute change after 60 months was minimal. The transient decreases in the Trial Outcome Index (TOI) score returned to their baseline levels. Use of ADT, presence of adverse events, and biochemical failure were related to lower scores. Scores of subdomains of FACT instruments indicated characteristic changes. The pattern of HRQOL change after C-ion RT was similar to that of other modalities. Further controlled studies focusing on a HRQOL in patients with prostate cancer are warranted.<br />学位の種類: 博士(医学). 報告番号: 甲第4242号. 学位記番号: 新大院博(医)甲第720号. 学位授与年月日: 平成29年3月23日<br />The Journal of Radiation Research 58(2)260-266,2017<br />新大院博(医)甲第720号 続きを見る
11.

論文(リポジトリ)

論文(リポジトリ)
Kobayashi, Makoto ; Suda, Takeshi ; Hashiba, Masao ; Nagasaki, Koji ; Adachi, Aiko ; Nomoto, Minoru ; Arakawa, Masaaki ; Aoyagi, Yutaka
出版情報: Acta medica et biologica — Acta medica et biologica.  56  pp.1-9,  2008-03.  Niigata University School of Medicine
本文リンク: http://hdl.handle.net/10191/19590
概要: Limitations to physical activity lead to impairments of insulin sensitivity and deterioration of health related quality of life (HRQOL) in patients with chronic liver diseases (CLD). The effects of regular exercise on physical and psychosocial factors were prospectively evaluated in CLD. Five patients with various etiologies and stages were enrolled. Daily aerobic and resistance trainings were conducted for a course of five months with an oral intake of branched-chain amino acids (BCAA) starting one month prior to the exercise. Various biochemical, physical parameters, and profile of mood states (POMS) were measured before and after the course. Statistical significance was evaluated using a resampling method. No event was marked during the course to require additional treatments. A significant improvement in insulin sensitivity was observed as reductions of fasting blood glucose and serum insulin levels. Physical capability was significantly improved in both strength and endurance as increments of grasping and knee extension powers, and ventilatory threshold. The fatigue score was significantly reduced in accordance with a decreasing tendency of all other negative aspects in POMS. While significant decreases in serum concentrations of cholinesterase and prealbumin, platelet count, and bone mass were observed, serum concentrations of transferrin and BCAA as well as prothrombin activity showed increasing tendency. Regular exercise could be a promising alternative to improve insulin sensitivity and HRQOL in CLD, though medications and close evaluation should be conducted for possibilities of osteoporosis and hemorrhagic events. 続きを見る
12.

論文(リポジトリ)

論文(リポジトリ)
FURUKAWA, Koichi ; WATANABE, Kazuhiko ; ABE, Yukihiro ; AIBA, Tuneo ; IKARASHI, Kentarou ; HATA, Koujiro ; Ho, Nichau ; TSUKIOKA, Satosi
出版情報: Acta medica et biologica — Acta medica et biologica.  53  pp.73-77,  2005-09.  Niigata University School of Medicine
本文リンク: http://hdl.handle.net/10191/1916
概要: To evaluate outpatient treatment, as well as the clinical effect of 1M tegafur-0.4M gimestat-1M otastat potassium(S-1) f ollowed by weekly Paclitaxel(PTX) for patients with far advanced inoperable gastric cancer, we analyzed retrospectively the appropriateness of outpatient anticancer chemotherapy from the standards of overall survival and time without symptom and toxicity(TWiST) as a quality-adjusted survival analysis. A total of 18 patients with advanced inoperable gastric cancer were treated with S-1 as first line single-agent chemotherapy from May 1, 2000 to September 30, 2000 at the Niigata City General Hospital. S-1 (60mg-120mg/m^2/orally twice daily on Days 1-28 followed by a 14 days rest/course) was repeated until progression of the disease. After the first line was completed, a second line, PTX (60mg-80mg/m^2/infused on Day 1/week, three weeks and withdrawal for a week), was started two weeks later. PTX was repeated until progression of the disease. No severe adverse events (≧National Cancer Institute Common Toxicity Criteria ((NCICTC) grade 3) were observed. The median survival time (MST) overall including the first line and second line was 295 days. The hospitalization period was 60.0 days throughout the median of the total hospital stay and the rate was 25.6% in overall survival. There was no significant difference by histological type, metastasis, liver metastasis, or peritoneal dissemination. The median duration of TWiST as quality-adjusted survival analysis was 353 days in good performance status (PS) and 72 days in poor PS. S-1 followed by weekly PTX for various advanced inoperable gastric cancers appears to be a promising, appropriate, and well-tolerated anticancer chemotherapy regimen in an outpatient setting. 続きを見る
13.

学位論文(リポジトリ)

学位
Sakai, Sayuri
出版情報: pp.1-18,  2015-03-23.  新潟大学
本文リンク: http://hdl.handle.net/10191/32281
概要: Background: Minamata disease (MD) is caused by the ingestion of a large amount of fish or shellfish contaminated with Me Hg included in industrial wastewater. In 1965, a number of cases were found along the Agano River in Niigata Prefecture in northern central Japan, which were collectively designated as “Niigata Minamata disease.” Patients with MD suffer from a set of complicated pains accompanied by various signs and symptoms. They also have mental and social pains, including loss of identity, stigmatization that lead leads to the refusal of friendship and marriage, and isolation in the local community. However, few studies have investigated the care and prevention measures required to relieve the symptoms of patients with MD. Aim: The objective of this survey was to investigate the symptoms, pain, and suffering experienced by patients with Niigata Minamata disease as well as their QOL and coping strategies. Design and setting: The survey was designed as a complete study of patients with MD accessible to the local government of Niigata Prefecture and that City. Results: The average score of the study subjects in the World Health Organization Quality of Life 26 (WHO/QOL-26) was considerably lower than that of the general population, while being female and having an occupation correlated with higher scores for some domains and/or overall QOL scores. The symptoms perceived by the subjects distressing in their daily lives included numbness in limbs, physical pain, disturbed sensory systems, limb dysfunctions, and fatigability. The measures commonly taken to relieve these symptoms included using medicines, taking a bath/going to springs, and maintaining warmth. The common emotional support included interpersonal relationships, emotional fulfillment, self-discipline in daily life, and bodily health. Those certified as having MD showed no significant difference in any domains and overall QOL. Conclusions: Palliative care providers should extend their targets for non-cancer palliative care and develop approaches for MD-specific total pain.<br />学位の種類: 博士(医学). 報告番号: 甲第3997号. 学位記番号: 新大院博(医)甲第643号. 学位授与年月日: 平成27年3月23日<br />新大院博(医)甲第643号 続きを見る
14.

論文(リポジトリ)

論文(リポジトリ)
生越, 章
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  126  pp.76-78,  2012-02.  新潟医学会
本文リンク: http://hdl.handle.net/10191/31396
概要: 骨肉腫を主体とする小児骨軟部肉腫患者の予後は飛躍的に改善している. 現在ではいかに救命するかだけでなく, いかに良好な quality of life (QOL) を達成するかも重要な問題である. 現在では小児骨軟部肉腫の多くには切断を回避 した患肢温存術が選択されるが, 特に人工関節置換術後には耐久性の問題から再手術の必要性が高く, また易感染性などの問題を含んでいる. 患肢を切断しても決して患者満足度やQOLは低くなく, 就業や結婚をへて高い社会活動性を維持している症例が多い. 続きを見る