3) 肝細胞癌の血清学的診断(シンポジウム 腫瘍抗原の臨床診断への応用, 第452回新潟医学会)

フォーマット:

論文(リポジトリ)

責任表示:

鈴木, 康史 ; 板谷, 啓司 ; 青柳, 豊 ; 小黒, 仁 ; 横田, 剛 ; 斉藤, 敦 ; 五十嵐, 健太郎 ; 上村, 朝輝 ; 朝倉, 均

出版情報:

新潟医学会, 1990-06

掲載情報:

新潟医学会雑誌 — 新潟医学会雑誌

ISSN:

00290440      

著者名:

鈴木, 康史

板谷, 啓司

青柳, 豊

小黒, 仁

横田, 剛

斉藤, 敦

五十嵐, 健太郎

上村, 朝輝

朝倉, 均

続きを見る

巻:

104

通号:

6

開始ページ:

465

終了ページ:

470

概要:

The serum concentration and degree of fucosylation (Fucosylation index) of alpha-fetoprotein (AFP) were determined in serum samples from 322 patients with hepatocellular carcinoma (HCC) and 155 with benign liver diseases (BLD). The serum concentration of PIVKA-II, sialyl SSEA (SLX) and CA-50 were also determined 60 with HCC and 60 with BLD. When the serum AFP concentration was below 1000ng/ml, there was no demarcation line between HCC and BLD. However, the … fucosylation index of AFP proved useful to discriminate HCC from patient with an increased concentration of AFP. On the other hand, positive reactions were noted in the following percentage of sera from HCC by PIVKA-II, 53% and SLX, 30%, respectively. It was concluded that the measurement of AFP concentration and of the fucosylation index together with PIVKA-II and SLX enable us to diagnose 88% of patients with HCC, serologically. 続きを見る

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