Search records | 新潟大学附属図書館 OPAC

概要: We investigated some peptidergic pathways in the extrageniculate visual system, by employing immunohistochemical and neural tracing methods. Tectogeniculate pathway was revealed to include some peptidergic projections. There were … Substance P (SP)-, vasoactive intestinal polypeptide- and/or cholecystokinin-immunoreactive projections in this pathway. These peptidergic projections occurred in the superficial layers of the superior colliculus (SC) and ended in the lateral part of the dorsal lateral geniculate nucleus. In the superficial layers of the SC, immunoreactivity for SP receptor was found in the projection neurons while not was seen in the intrinsic neurons. This means outputs from the SC, which primarily could be driven by retinal inputs, are under control of SP. Though the source of SP has not been claified yet, SP neurons in the SC seem to be one source. In the pretectum, a special region where SP receptors were densely distributed was found. This region had few retinal inputs. SP receptor immunoreactive neurons in this region were revealed to have commissural projections, such as to the contralateral pretectum and SC. 続きを見る

概要: The relationship between the visual cortex and superior colliculus (SC) is integral in the elaboration of visually-guided behaviors. Although numerous regions of visual cortex send projections to SC, the lateral suprasylvian (LS) … cortex is known to be a primary source of direct visual cortical afferents to the deep laminae of SC, in which tectospinal neurons are located. Our recent experiments provide anatomical and physiological evidence to support the idea that, in addition to a direct influence on deep lamina neurons, LS may modulate tectospinal neurons indirectly via its projection to the striatum. 続きを見る

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