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図書 |
研究代表者星野嘉恵子
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論文(リポジトリ) |
目黒, 玲子 ; 星野, 嘉恵子 ; 松岡, 勝人 ; 白, 万柱 ; 車田, 正男
概要:
We investigated some peptidergic pathways in the extrageniculate visual system, by employing immunohistochemical and neural tracing methods. Tectogeniculate pathway was revealed to include some peptidergic projections. There were
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Substance P (SP)-, vasoactive intestinal polypeptide- and/or cholecystokinin-immunoreactive projections in this pathway. These peptidergic projections occurred in the superficial layers of the superior colliculus (SC) and ended in the lateral part of the dorsal lateral geniculate nucleus. In the superficial layers of the SC, immunoreactivity for SP receptor was found in the projection neurons while not was seen in the intrinsic neurons. This means outputs from the SC, which primarily could be driven by retinal inputs, are under control of SP. Though the source of SP has not been claified yet, SP neurons in the SC seem to be one source. In the pretectum, a special region where SP receptors were densely distributed was found. This region had few retinal inputs. SP receptor immunoreactive neurons in this region were revealed to have commissural projections, such as to the contralateral pretectum and SC.
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3.
論文(リポジトリ) |
星野, 嘉恵子 ; 周, 宜興 ; 車田, 正男
概要:
The lateral posterior complex (LP) of the thalamus receives a variety of different inputs from cortical and subcortical
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areas. We have previously demonstrated four types of vesicle containing profiles in this complex, and have identified GABA-ergic terminals. In this study, we examined the features by the light and electron microscopy of the immunoreactivity with antibodies raised against aspartate (Asp), glutamate (Glu), GABA, choline acetyltransferase (ChAT) and substance P (SP) in the LP complex. The following observations were found:(1) Asp and Glu;immunolabeled neurons were medium sized. Immunolabeled terminals were medium sized containing round vesicles and making asymmetrical synaptic contacts with dendritic profiles. (2) GABA;immunolabeled neurons were small. Immunolabeled terminals were small, contained pleomorphic synaptic vesicles and forming symmetrical synaptic contacts with dendritic profiles. (3) ChAT;no ChAT immunolabeled neurons were found. Immunolabeled terminals were small, and contained round vesicles making en passant, symmetrical and asymmetrical synaptic contacts with dendritic profiles. (4) SP;immunolabeled neurons were medium sized. Immunolabeled terminals were small containing round vesicles, and asymmetrical synaptic contacts with dendritic profile.
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4.
論文(リポジトリ) |
星野, 嘉恵子
概要:
Nucleolar sizes of the amygdaloid neurons in Nissl preparations from opossum, mole, rat, tupia, bat, cat, howling monkey
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, woolly monkey, macaque, chimpanzee and human were measured using a computerized image analyzer (Videoplan, Contron). The neurons in lateral (M), intermediate (T') and medial (T) principal subnuclei, central (E) and intercalated (K) subnuclei were examined, resulting in the followings : 1) The increasing order of the width of the nucleolar size distribution in every of these four subnuclei was found to be rat→cat→macaque→chimpanzee→human, which roughly corresponds to the ascending order of mammalian phylogeny. Two different types of this widening feature in nucleolar size distribution were identfied. One (T', T) tends to progressively become composed of separate two, rather homogeneous populations with large and small nucleoli, and the other (M, E) is composed of a whole, heterogeneous population. 2) In the cases of T' and T subnuclei, the ratio of the population with small nucleolei to the whole population was found to increase with the phylogenetic ascent, which seemed to result from the increasement in the population of Golgi 11 type cells. 3) In the cases of M and E subnuclei, the heterogeneity seemed to be largely due to multiplication of the sorts of Golgi II type cells. 4) Contrary to that the functional division of amygdaloid complex into two parts is based on a boundary between intermediate and medial principal subnuclei, these two subnuclei showed marked similarity with each other with respect to nucleolar size distribution and their phylogenetic tendencies. Accordingly, from a phylogenetic viewpoint of neuronal organization, these results suggested that the functional boundary should be redefined between lateral and intermediate principal subnuclei.
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5.
論文(リポジトリ) |
芹澤, 正博 ; 星野, 嘉恵子 ; 平野, 茂樹 ; 車田, 正男
概要:
Projections from the visual cortical areas to the striatum and superior colliculus are believed to play integral roles in visual attentive and orienting behaviors. In the cat, the direct corticotectal and indirect corticostriatal
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(via the substanita nigra) projections of the lateral suprasylvian cortex (LS) are thought to converge on neurons situated in the deep laminae of the superior colliculus and exert their influences via the outputs of the superior colliculus (Norita et. '91).
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6.
論文(リポジトリ) |
星野, 嘉恵子
概要:
Size distributions of nucleolar areas of the neurons in the intermediate principal nucleus of amygdaloid complex were studied by using a computerized image analyzer (Videoplan, Contron). In Golgi preparations from cat, two cell
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types were distinguished in this nucleus: a large spiny neuron (Golgi I type), and a small spine-sparse one (Golgi II type). Golgi I and II type cells found in these Golgi preparations were clipped, embedded in Epon, cut into thin sections, and the sizes of their nucleoli were measured. The distribution of nucleolar sizes demonstrated that the Golgi I type cell had a large nucleolus and the Golgi II type cell had a small one. Nucleolar sizes of the neurons in the intermediate principal nucleus were measured in Nissl preparations from cat, rat, tupaia, opossum, howling monkey, woolly monkey, chimpanzee and man. The result showed the existence of a neuronal group with a large nucleolus and one with a small nucleolus, except for the rat. The groups were considered to correspond to Golgi I and II type cells, respectively. The neurons corresponding to Golgi I type cells become larger with phylogenetic ascent. Those corresponding to Golgi II type cells, however, are identical. in all animals, and these nucleolar sizes coincide with the ones of the intercalated nucleus.
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7.
論文(リポジトリ) |
星野, 嘉恵子
概要:
The lateral principal nucleus of amygdaloid complex, at the lateral border and the ventral part, is demonstrated to contain zinc by the sulfide silver method of Timm. We studied on the origin of the terminals in the positions showing a
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positive reaction with the method of Timm by using HRP and Nauta methods. The injections of horseradish peroxidase (HRP) were made into the lateral principal nucleus. Labeled regions by HRP were coagulated electrically, and the degenerating fibers in the lateral principal nucleus were examined. It is shown that the lateral principal nucleus of amygdaloid complex has many afferent fibers from piriform cortex in agreement with the fields showing a positive reaction by the Timm method.
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8.
図書 |
星野嘉恵子
目次情報:
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