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機能性下垂体腺腫の境界部組織(pseudocapsule)の免疫組織化学的研究

フォーマット:
論文(リポジトリ)
責任表示:
田村, 哲郎
出版情報:
新潟医学会, 1992-11
掲載情報:
新潟医学会雑誌 = 新潟医学会雑誌
ISSN:
00290440  CiNii Research  Webcat Plus  JAIRO
著者名:
田村, 哲郎  
巻:
106
通号:
11
開始ページ:
1036
終了ページ:
1040
バージョン:
publisher
概要:
In order to investigate the pseudocapsule, histological and immunohistochemical studies were performed on adenomas and pseudocapsules or periadenomatous pituitary glands obtained from 61 pituitary operations (acromegaly 34, prolactinoma 19, Cushing's disease 8). The pseudocapsule was observed in 41 cases (67.2%). The incidence was higher in acromegaly (26/34, 76.5%) than prolactinoma (13/19, 68.4%) and Cushing's disease (2/8, 25.0%). Histologically, the pseudocapsule was the tissue composed of the compressed alveolar structure with fibrosis. Immunohistochemistry demonstrated that many kinds of anterior pituitary hormone positive cells were scattered in the pseudocapsule. Some pseudocapsule (9/41, 22.0%) partly contained adenoma cells. From these observations, it is concluded that the pseudocapsule is mainly composed of normal pituitary gland compressed by the tumor. Pseudocapsulectomy after selective adenomectomy is recommended to achieve endocrinological cure in the treatment of the functioning pituitary adenomas. 続きを見る
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