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大腸癌・腺腫の病理形態学的検討 : 癌・腺腫の肉眼鑑別と癌の組織発生について

フォーマット:
論文(リポジトリ)
責任表示:
味岡, 洋一
出版情報:
新潟医学会, 1990-02
掲載情報:
新潟医学会雑誌 = 新潟医学会雑誌
ISSN:
00290440  CiNii Research  Webcat Plus  JAIRO
著者名:
味岡, 洋一  
巻:
104
通号:
2
開始ページ:
131
終了ページ:
142
バージョン:
publisher
概要:
Macroscopic differential diagnosis between adenoma and carcinoma and histogenesis of carcinoma of the colon and rectum were studied on 2102 advanced carcinomas, early carcinomas and adenomas. For the macroscopic differential diagnosis, size and gross configuration of lesions played important roles. Any lesions more than 30mm in size, polypoid lesions more than 25mm, and depressed lesions more than 10mm were advanced carcinomas. Excluding the advanced cancers, it would be reasonable to consider the following lesions as submucosal carcinomas, i.e. depressed or sessile lesions more than 15mm in size and the subpedunculated more than 20mm. Flat or pedunclulated lesions had less possibility of being submucosal carcinomas, and they were intramucosal carcinomas, at the size of more than 10mm. Submucosal carcinomas were well diagnose macroscopically by their characteristics of surface appearance at the accuracy of 73.1%. For the histogenesis of the colorectal carcinomas, 75.9-85.3% of intramucosal carcinomas were estimated to originate from benign adenoma. The malignancy rate of adenomas were affected by their size. It showed rapid increase in proportion to size until 15mm, and reached the plateau at the size of more than 15mm. 続きを見る
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