close
1.

Article

Article
Ishihara, Akihiko ; Itoh, Kazuo ; Itoh, Minoru ; Hirofuji, Chiyoko ; Hayashi, Hitomi
Published: Acta medica et biologica — Acta medica et biologica.  46  pp.1-6,  1998-03.  Niigata University School of Medicine
Full Text Link: http://hdl.handle.net/10191/33071
Abstract: Fiber type distributions of the fast-twitch extensor digitorum longus muscle in rats were examined after exposure to hypobaric-hypoxia for 5 weeks from the postnatal age of 5 weeks or for 10 weeks from the postnatal age of 10 weeks. Muscle fibers were classified into fast-twitch oxidative glycolytic (FOG), fast-twitch glycolytic (FG), or slow-twitch oxidative (SO). The percentage of FOG fibers was increased and that of FG fibers was decreased in the hypoxic rats at 10 weeks of age, while there was no difference in the percentage of SO fibers between the normoxic and hypoxic rats. There was no difference in the fiber type distribution between the normoxic and hypoxic rats at 20 weeks of age. These results indicate an age-specific response of hypobarichypoxia on the fiber types of the rat extensor digitorum longus muscle. Read more
2.

Article

Article
Ishihara, Akihiko ; Itoh, Kazuo ; Itoh, Minoru ; Hirofuji, Chiyoko ; Hayashi, Hitomi
Published: Acta medica et biologica — Acta medica et biologica.  44  pp.221-225,  1996-12.  Niigata University School of Medicine
Full Text Link: http://hdl.handle.net/10191/33185
Abstract: The histochemical type shift of fibers from fast-twitch oxidative glycolytic (FOG) to slow-twitch oxidative (SO) in the rat soleus muscle occurs during postnatal development. Our recent experiments demonstrated that the type shift of fibers from FOG to SO is inhibited by hypobaric-hypoxia. Furthermore, the present study has shown that hypobaric-hypoxia inhibits the growth-related type shift of fibers from FOG to SO in the rat soleus muscle, irrespective of the duration of exposure to hypobaric-hypoxia. Read more