| 1.
論文(リポジトリ) |
論文(リポジトリ)
|
佐藤, 正之 ; 村川, 英三
概要:
To diagnose DIC, we have always been looking for new parameters: e.g. fibrinogen and fibrin degradation products (FDP),
…
antithrombinIII (ATIII), α_2 plasmin inhibitor (α_2PI), fibrinmonomer complex (FM) and D dimer (D-D). But these parameters have many problems: FDP can not distinguish between primary fibrinolysis and secondary fibrinolysis. With low plasma levels of ATIII and α_2PI, we can not see they are due to comsumption or due to reduced production. FM is not quantitative analysis. D-D which is specific for secondary fibrinolygis, is too sensitive to assess secondary fibrinolysis in DIC. We evaluated new molecular markers for the diagnosis of DIC in acute promyelocytic leukemia and other disorders: Thrombin antithrombin III complex (TAT) and plasmin・α_2 plasmin inhibitor complex (PIC). TAT and PIC were extremely elevated even though in probable DIC group with DIC scor<4. Abnormal findings of these parameters in probable DIC group seem to show hypercoagulability and fibrinolysis in this group. So plasma levels of TAT and PIC for the diagnosis of DIC should be established. With our data, plasma levels of both TAT≧7.5μg/l and PIC≧2.5μg/ml, three times of normal value, are valuable for the diagnosis of DIC. Recently the therapy of DIC has greatly advanced using synthetic protease inhibitors and ATIII concentrate.
続きを見る
|
||||
| 2.
論文(リポジトリ) |
論文(リポジトリ)
|
水野, 祐子 ; 桜井, 友子 ; 中川, 利子 ; 佐藤, 正之 ; 村川, 英三 ; 笹崎, 義博 ; 浅見, 恵子 ; 内海, 治郎
|
||||
| 3.
論文(リポジトリ) |
論文(リポジトリ)
|
佐藤, 正之 ; 村川, 英三
概要:
Two hundred sixteen cases with non-Hodgkin's lymphoma which had been treated in Niigata Cancer Center Hospital from January 1978 to December 1987 were investigated in this paper. In cases with nodural lymphoma, 5 year survival
…
rates were 42.6% in stage I+II and 16.4% in stage III+IV. With Waldeyer lymphom, 5 year survival were 50.4% in stage I+II and 0% in stage III+IV. 5 year survival were 37.7% in cases with stage I+II of extranodular lymphoma without gastrointestinal lymphoma and 15.9% in stage III+IV respectively. 5 year survival rate were steadily improved compared with that in 102 cases which had been treated in 10 years prior this study. It became clear that prognostic factors for survival were much depended on primary site, clinical stage, histopathological type, surface marker and sex. Therefore, a new ideal protocol for treatment of non-Hodgkin's lymphoma including above mentioned factors should be considered.
続きを見る
|
||||
| 4.
論文(リポジトリ) |
論文(リポジトリ)
|
中川, 利子 ; 斉藤, ひろこ ; 川崎, 幸子 ; 水野, 祐子 ; 神田, 綾子 ; 平野, 久美 ; 渡辺, 泰男 ; 佐藤, 正之 ; 村川, 英三
|
||||
| 5.
論文(リポジトリ) |
論文(リポジトリ)
|
佐藤, 正之 ; 村川, 英三
|
||||
| 6.
論文(リポジトリ) |
論文(リポジトリ)
|
佐藤, 正之 ; 高橋, 滋 ; 村川, 英三
|
||||
| 7.
論文(リポジトリ) |
論文(リポジトリ)
|
村川, 英三 ; 佐藤, 正之 ; 内海, 治郎 ; 浅見, 恵子 ; 橋本, 謹也 ; 桜井, 友子
|
||||
| 8.
論文(リポジトリ) |
論文(リポジトリ)
|
梅田, ひろ子 ; 桜井, 友子 ; 神田, 綾子 ; 牧, ちづ子 ; 斉藤, 博司 ; 中川, 利子 ; 渡辺, 泰男 ; 佐藤, 正之 ; 村川, 英三
|
||||
| 9.
論文(リポジトリ) |
論文(リポジトリ)
|
村川, 英三 ; 佐藤, 正之
概要:
Two hundred twenty-six patients with non-Hodgkin's lymphoma admitted to the Cancer Center Niigata Hospital between January 1978 and December 1987 are reviewed. In total, survival rate of the patients has been markedly improved,
…
compaired with the one of the patients, who were admitted between 1968 and 1978. Respectively, survival rate and response to treatment are significantly aggravated by various clinicopathological factors, such as 1) sex of male, 2) primary site of lymph-node, 3) advanced clinical stage, 4) histopathological type of either diffuse large cell type or diffuse pleomorphic type and 5) surface marker of T. To the patients with NHL of gastrointestinal tracts and Waldeyer's ring, aggressive combination chemotherapies are usefull even in early stages. Standardization of principles and protocols of treatment for each of the clinicopathological types of NHL is expeccted.
続きを見る
|
||||
| 10.
論文(リポジトリ) |
論文(リポジトリ)
|
桜井, 友子 ; 水野, 祐子 ; 中川, 利子 ; 佐藤, 正之 ; 村川, 英三 ; 橋本, 謹也 ; 浅見, 恵子 ; 内海, 治郎
|
