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1.

論文(リポジトリ)

論文(リポジトリ)
松本, 康男
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  123  pp.111-116,  2009-03.  新潟医学会
本文リンク: http://hdl.handle.net/10191/28277
概要: Purpose: Stereotactic radiotherapy (SRT) has been increasingly performed to treat peripheral Stage I non-small cell lung cancer (NSCLC) in many institutions. The preliminary results of treatment of Stage T1-T3N0M0 lung cancer using the Novalis radiotherapy system were analyzed. Method & Materials: Between July 2005 and June 2007, 185 patients with primary lung cancer were treated with the Novalis system. Excluding patients with local recurrence (post-operative or post-irradiation), advanced disease and poor performance status (KPS≧3), 141 patients (146 lesions) are the subject of this report. The disease was staged as T1N0M0, T2N0M0 and T3N0M0 in 101, 41 and 4 patients, respectively. SRT was performed using coplanar dynamic conformal arcs. All patients were received 48Gy to 60Gy (4 to 10 fractions) at the isocenter. Results: During follow up (median, 16.0 months; range, 3-31 months), pulmonary complications of National Cancer Institute-Common Toxicity Criteria (NCI-CTC) Grade≧2 were observed in 4 patients. Local progression occurred in 11 patients (7.6%), The 1-year&2-year overall survival rates were 96.2&92.0%, respectively. Conclusions: SRT using the Novalis shaped beam radiotherapy system is an effective and safe noninvasive treatment modality for early stage NSCLC. 続きを見る
2.

論文(リポジトリ)

論文(リポジトリ)
吉澤, 弘久
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  120  pp.425-429,  2006-08.  新潟医学会
本文リンク: http://hdl.handle.net/10191/19862
概要: Lung cancer is the leading cause of cancer mortality in the world. In Japan, lung cancer was responsible for 41634 of men and 15086 of women death in 2003, accounting for 18.3% of all cancer death each year and approximately 100,000 death will occur in 2010. Despite chemotherapy with new agents have been shown to improve the survival and quality of life in patients with lung cancer, curable patient is still rare. Molecular target therapy, cellular therapy could be powerful arms to overcome this stagnant situation. Moreover, combination of these treatment modalities, i.e., multimodality therapy should improve the prognosis of patients with lung cancer. 続きを見る
3.

論文(リポジトリ)

論文(リポジトリ)
滝沢, 恒世 ; 羽賀, 学 ; 小池, 輝明 ; 寺島, 雅範
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  113  pp.399-401,  1999-09.  新潟医学会
本文リンク: http://hdl.handle.net/10191/46834
概要: Our aim in this study is to evaluate the usefulness of thoracoscopic approach in lobectomy for patients with lung cancer . The number of using analgesic agents was counted in 10 patients who underwent thoracoscopic lobectomy for lung cancer and compared with that in another 10 patients who underwent standard lobectomy. The number in patients underwent thoracoscopic lobectomy was 1.8±1.5 times, while that in those underwent standard lobectomy was 10.8±2.1 times. The difference was statistically significant. However, we believe, more evidences are necessary to insist that thoracoscopic approach is beneficial to patients with lung cancer undergoing lobectomy. 続きを見る
4.

論文(リポジトリ)

論文(リポジトリ)
滝沢, 恒世 ; 寺島, 雅範 ; 小池, 輝明 ; 赤松, 秀樹
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  109  pp.329-331,  1995-07.  新潟医学会
本文リンク: http://hdl.handle.net/10191/42514
概要: Nine patients with clinical stage T1NOMO lung cancer underwent video-assisted thoracic surgery (VATS) for lobectomy with mediastinal lymph node dissection. There were no major complications. We belive that a complete operation can be done by VATS for stage 1 lung cancer. 続きを見る
5.

論文(リポジトリ)

論文(リポジトリ)
斎藤, 眞理 ; 清野, 康夫 ; 植松, 孝悦 ; 栗田, 雄三 ; 横山, 晶
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  109  pp.332-337,  1995-07.  新潟医学会
本文リンク: http://hdl.handle.net/10191/42515
概要: In comparison with operation, we observed more recurrence after external beam radiotherapy for roentogenographically occ ult lung cancer. Then, since July 1991, we have treated that lung cancer, with external beam radiotherapy and intraluminal afterloading irradiation using ^<192>Iridium thin wire. The indication of this method is roentogenographically occult lung cancer, diagnosed inoperable for their respiratory function, age, and complications, and for refusal of operation. Up to Sept. 1994, 36 patients (44 lesions) were treated by this method. The follow-up period ranged from 0 to 41 months. Recurrence occured in 2 cases on whom an operation was done:one is well and the other is alive with disease. Radiation pneumonitis required treatment was observed in another 2 cases. Other recurrence or severe complications from irradiation have not been observed. We think this treatment is effective for roentogenographically occult lung cancer. 続きを見る
6.

論文(リポジトリ)

論文(リポジトリ)
島田, 克己
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  102  pp.667-671,  1988-11.  新潟医学会
本文リンク: http://hdl.handle.net/10191/41022
概要: Mass screening for early detection of lung cancer is now spreading in Japan. In Niigata Prefecture, mass screening progr ams were performed in 47 out of 122 districts in 1985. From 1983 to 1985, 53 cases of lung cancer were detected by mass screening fluorography intended for early detection of pulmonary tuberculosis in Niigata city. The incidence was 48 per 100,000. From the analysis of our data, it was concluded that double reading of X-ray films and comparison with previous ones were very important. Some other aspects of mass screening of lung cancer including sputum cytology were also discussed. 続きを見る
7.

論文(リポジトリ)

論文(リポジトリ)
鈴木, 栄一 ; 来生, 哲 ; 荒川, 正昭 ; 五十嵐, 謙一 ; 原口, 通比古
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  107  pp.959-966,  1993-11.  新潟医学会
本文リンク: http://hdl.handle.net/10191/37802
概要: The respiratory system is divided into the two partitions, the conducting airway and the terminal respiratory unit. The former is also subdivided into the upper and lower airways. In this symposium, we discussed the respiratory disoders, particularly, in the lower airway and terminal respiratory unit, in elderly people. These disorders included the physiological aging changes and the diseases related to aging, including chronic pulmonary emphysema, idiopathic interstitial pneumonia, bacterial pneumonia and primary lung cancer. 続きを見る
8.

学位論文(リポジトリ)

学位
Yamazaki, Motohiko
出版情報: 2015-03-23.  新潟大学
本文リンク: http://hdl.handle.net/10191/32260
概要: Objectives: To assess the prognostic value of combined evaluation of preoperative CT findings and pre/postoperative seru m carcinoembryonic antigen (CEA) levels for pathological stage I lung adenocarcinoma. Methods: This retrospective study included 250 consecutive patients who underwent complete resection for <__-3-cm pathological stage I (T1–2aN0M0) adenocarcinomas (132 men, 118 women; mean age, 67.8 years). Radiologists evaluated following CT findings: maximum tumor diameter, percentage of solid component (%solid), air bronchogram, spiculation, adjacency of bullae or interstitial pneumonia (IP) around the tumor, notch, and pleural indent. These CT findings, pre/postoperative CEA levels, age, gender, and Brinkman index were assessed by Cox proportional hazards model to determine the best prognostic model. Prognostic accuracy was examined using the area under the receiver operating characteristic curve (AUC). Results: Median follow-up period was 73.2 months. In multivariate analysis, high %solid, adjacency of bullae or IP around the tumor, and high postoperative CEA levels comprised the best combination for predicting recurrence (P < 0.05). A combination of these three findings had a greater accuracy in predicting 5-year disease-free survival than did %solid alone (AUC = 0.853 versus 0.792; P = 0.023), with a sensitivity of 85.7% and a specificity of 74.3% at the optimal threshold. The best cut-off values of %solid and postoperative CEA levels for predicting high-risk patients were >__-48% and >__-3.7 ng/mL, respectively. Conclusion: Compared to %solid alone, combined evaluation of %solid, adjacency of bullae or IP change around the tumor, and postoperative CEA levels improves recurrence prediction for stage I lung adenocarcinoma.<br />学位の種類: 博士(医学). 報告番号: 甲第3976号. 学位記番号: 新大院博(医)甲第622号. 学位授与年月日: 平成27年3月23日<br />European Journal of Radiology. 2015, 84(1), 178-184.<br />新大院博(医)甲第622号 続きを見る