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図書

図書
柴原浩章編著
出版情報: 東京 : 中外医学社, 2019.11
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電子ブック

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柴原浩章編著
出版情報: 東京 : 中外医学社, 2019.11
本文リンク: https://elib.maruzen.co.jp/elib/html/BookDetail/Id/3000085394
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論文(リポジトリ)

論文(リポジトリ)
高桑, 好一 ; 横尾, 朋和 ; 大木, 泉 ; 能仲, 太郎 ; 石井, 桂介 ; 菊池, 朗 ; 田中, 憲一 ; 田村, 正毅
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  120  pp.564-568,  2006-10.  新潟医学会
本文リンク: http://hdl.handle.net/10191/19936
4.

論文(リポジトリ)

論文(リポジトリ)
高桑, 好一 ; 石井, 桂介 ; 安達, 博 ; 三井, 卓弥 ; 東野, 昌彦 ; 田中, 憲一 ; 田村, 正毅
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  115  pp.241-244,  2001-06.  新潟医学会
本文リンク: http://hdl.handle.net/10191/48259
概要: It has been suggested recently that autoimmune mechanisms are implicated in the genesis of adverse outcome of pregnancy such as spontaneous abortion, intrauterine fetal death (IUFD), intrauterine growth retardation (IUGR), and preeclampsia. In particular anti-phospholipid antibodies (APA) are considered to be linked to the manifestations of such complication of pregnancy. In order to elucidate the association between the APA and the genesis of above-mentioned adverse pregnancy more clearly, we demonstrated following data in this paper. 1.The positive rate of APA in patients with recurrent fetal wastage or patients with severe preeclampsia was significantly higher compared with that in normal control women. 2.The rate of occurrence of spontaneous abortion, IUFD, IUGR, and preeclampsia was significantly higher in the APA-positive group compared with that in the APA negative group by the prospective study in which APA were screened at the first trimester of pregnant women. In addition to such data, the mechanisms of the genesis of adverse pregnancy by APA, and the effective treatment for such patients were discussed in this paper. 続きを見る
5.

論文(リポジトリ)

論文(リポジトリ)
吉谷, 徳夫 ; 高桑, 好一 ; 金沢, 浩二 ; 田中, 憲一
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  104  pp.925-932,  1990-11.  新潟医学会
本文リンク: http://hdl.handle.net/10191/35093
概要: Today, the definition of abortion is the loss of pregnancy in less than 24 gestational weeks, and that of premature labor is the delivery from 24 to less than 37 gestational weeks by Japan Society of Obstetrics and Gynecology. Recent progress in medical electro-techniques has given a remarkable advance in clinical assessment and management of pregnancy. Also, patient with habitual fetal wastage due to immunologic etiology has been successfully treated by alloimmunization using partner's lymphocytes. In this paper, change in definition of abortion and premature labor, advance in diagnosis and management of abortion, and immunological habitual abortion were reviewed. 続きを見る
6.

論文(リポジトリ)

論文(リポジトリ)
石田, 道雄
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  106  pp.824-835,  1992-09.  新潟医学会
本文リンク: http://hdl.handle.net/10191/39953
概要: In order to establish the appropriate way of the counselling for couples with chromosomal aberration and recurrent or habitual abortion, the more substantial method for the prediction of pregnant prognosis in these patients was sought from the results of genetic counselling performed at genetic counselling outpatient clinic, department of obstetrics and gynecology, Niigata University School of Medicine, between April, 1982 and April, 1991. The results were as follows: 1) Out of 104 couples with recurrent abortion who were offered genetic counselling during indicated period at our outpatient clinic, in 29, the chromosomal aberration was observed. 2) Of twenty-nine couples, in 15, the wives were carriers, and in remaining 14, the husbands were carriers. 3) The chromosomal aberrations included 12 cases of reciprocal translocation, 6 cases of Robertsonian translocation, 4 cases of pericentric inversion, 4 cases of sex chromosome aneuploidy, 1 case of 14 p^+, 1 case of 22 p^+ and 1 case of Yq^+. 4) Relatively high rates of spontaneous abortion were obatained by accumulation of past pregnant history in patients with chromosomal aberration compared with the theoretical risks of abortion. 5) Application of empiric risks was considered to be more approapriate and practical for predicting the prognosis of further pregnancy for the couples of recurrent or habitual abortion with chromosomal aberration. 続きを見る
7.

論文(リポジトリ)

論文(リポジトリ)
高桑, 好一 ; 後藤, 重則 ; 長谷川, 功 ; 加藤, 美和子 ; 梶野, 徹 ; 源川, 雄介 ; 吉沢, 浩志 ; 佐藤, 芳昭 ; 金沢, 浩二 ; 竹内, 正七 ; 菊池, 正俊 ; 佐藤, 健比呂 ; 長尾, 政之助 ; 荒川, 正昭 ; 徳永, 昭輝
出版情報: 新潟医学会雑誌 — 新潟医学会雑誌.  102  pp.108-111,  1988-02.  新潟医学会
本文リンク: http://hdl.handle.net/10191/40627
概要: The management of pregnant women complicated with autoimmune disease is one of the most important issues for obstetricians. It is well-known that the reproductive performance is tend to be poor in patients with autoimmune disease, especially in patients with systemic lupus erythematosus. In this context we investigated the outcome of pregnancy in patients with autoimmune disease, mainly in patients with SLE. Out of 29 pregnant women with SLE allowed to continue their pregnancy, in 6 cases pregnancy had resulted in stillbirth, and in 2 it had resulted in early spontaneous abortion, thus in 27.6% of them the pregnancy had resulted in fetal miscarriage. In prenatal course, 28.8% of patients with SLE had showed deterioration of the disease, and 9.6% of them had showed after the termination of their pregnancy. Out of 27 babies delivered by mother with SLE, only 12 babies (44.4%) were born as appropriate-for-date-baby, and 7 babies (26.0%) were dead either before or after delivery. These data clearly demonstrated the necessity of careful observation and management of the pregnant women with SLE. In addition to these investigations, we examined the autoimmune aspects of patients with recurrent fetal wastage. Out of 62 patients, in 11 cases the antinuclear antibodies (ANA) were observed in their serum, and especially secondary recurrent aborters revealed high incidence of positive ANA, suggesting the existence of subclinical autoimmune disease in patients with recurrent fetal wastage. 続きを見る