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4) 核医学画像診断の進歩 : 脳血流シンチSPECT(シンポジウム 画像診断 : 最近の進歩, 第438回新潟医学会)

フォーマット:
論文(リポジトリ)
責任表示:
小田野, 幾雄
出版情報:
新潟医学会, 1989-03
掲載情報:
新潟医学会雑誌 = 新潟医学会雑誌
ISSN:
00290440  CiNii Articles  Webcat Plus  JAIRO
著者名:
小田野, 幾雄  
巻:
103
通号:
3
開始ページ:
171
終了ページ:
175
バージョン:
publisher
概要:
The imaging of cerebral metabolism is important for diagnosis and treatment of cerebral vascular disorders. Recently, single photone emission computed tomography (SPECT) and new several radio-pharmaceuticals have been developed for cerebral metabolic imaging. Especially, one of the most usefull radio-pharmaceuticals is N-isopropyl-p (^<123>I) iodoamphetamine (IMP). There is still more unknown portion in tracer kinetics of ^<123>I-IMP, though, it is thought to be true that early SPECT images of ^<123>I-IMP show the distribution of regional cerebral blood flow. And it is also an advantage of ^<123>I-IMP to be able to measure regional cerebral blood flow (rCBF) by the modified arterial blood sampling method. On early SPECT images of ^<123>I-IMP in the ischemic cerebral vascular disorders, the low perfusion area usually consists of three or four parts differing in severity. The regional blood flow (rCBF) of the area corresponding to the low density area, peri-low density area and normal density and low perfusion area on X-ray CT are 15ml/100g・brain/min, 34ml/100g・brain/min and 46ml/100g・brain/min, respectively. The redistribution phenomenone is frequently observed on delayed ^<123>I-IMP SPECT images. This phenomenone is especially observed in the area in which rCBF is between 25 to 35ml/100g・brain/min. 続きを見る
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関, 耕治, 湯浅, 龍彦, 川瀬, 康裕, 山本, 恒男

新潟医学会